Rabbit Anti-Ret/HSCR1 antibody說明書

 ABCAM

Catalog Number :RS-6270R

Quantity size :   0.1ml （dilute with pH 7.4    0.01 M PBS or antibody diluent ）background:
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].

Specificity : 

–Anti-Ret/HSCR1 is a rabbit polyclonal antibody              

–specific for anti-Ret/HSCR1 of  rat ,mo ,hu

– use for western blotting,elisa,immunoprecipitation and immunohistochemistry

–Protein G affinity chromatography purification, purity :>95%

– Isotype:  IgG

– mol wt:  124 kDa

Application :  

• WB=1:100-500  
• ELISA=1:500-1000
•  IHC-P=1:100-500  
• IHC-F=1:100-500 

–  not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..

Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.