英文名稱	Myeloperoxidase
中文名稱	髓過氧化物酶抗中性粒細胞胞質IgG抗體
別名	Myeloperoxidase; MPO; c-ANCA; 89 kDa myeloperoxidase; 84 kDa yeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain; EC 1.11.1.7; PERM_HUMAN.
說明書	0.1ml 0.2ml
研究領域	腫瘤細胞生物免疫學激酶和磷酸酶淋巴細胞
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig,
產品應用	WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	77kDa
細胞定位	細胞漿
性狀	Lyophilized or Liquid
濃度	1mg/1ml
免疫原	KLH conjugated synthetic peptide derived from human Myeloperoxidase
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產品介紹	background: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008]. Function: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Subunit: Tetramer of two light chains and two heavy chains. Subcellular Location: Lysosome.