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【產(chǎn)品名稱】：Anti-Androgen receptor抗體,雄激素受體抗體（實(shí)驗(yàn)）
【產(chǎn)品編號】：BYK-0118R
【產(chǎn)品規(guī)格】：0.1ml/0.2ml
【產(chǎn)品價格】：詢價（電詢或客服）
【抗體來源】：Rabbit OR Mouse or Goat
【產(chǎn)品用途】：科研實(shí)驗(yàn)，用于ELISA實(shí)驗(yàn)、免疫組化實(shí)驗(yàn)，WB實(shí)驗(yàn)，IF實(shí)驗(yàn)等，可，索取產(chǎn)品說明書！
【性 狀】： Lyophilized or Liquid
【濃 度】： 1mg/1ml
【亞 型】： IgG
【貯 存】： 貯存于-20℃.
【相關(guān)標(biāo)記】：HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【產(chǎn)品別名】：AIS; AIS; ANDR_HUMAN; Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); Androgen receptor; AR; DHTR; Dihydro Testosterone Receptor; Dihydrotestosterone receptor; HUMARA; HYSP1; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; Spinal and bulbar muscular atrophy; TFM.
【產(chǎn)品介紹】：The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
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