背景資料

Oleoyl ethanolamide （OEA） is an analog of the endocannabinoid AEA found in brain tissue and in chocolate. It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue， but its biosynthesis is reduced in the intestine of rats following food deprivation. OEA is an endogenous， potent agonist for PPAR.alpha.， exhibiting an EC50 value of 120 nM in a transactivation assay. Systemic administration of OEA suppresses food intake and reduces weight gain in rats （10 mg/kg intraperitoneally） and PPAR.alpha. wild-type mice， but not in PPAR.alpha. knockout mice. These data indicate that OEA regulates food intake by a PPAR.alpha.-mediated mechanism.

產品描述

An analog of the endocannabinoid AEA found in brain tissue and in chocolate whose biosynthesis is reduced in the intestine of rats following food deprivation； an endogenous， potent agonist for PPARα （EC50 = 120 nM in a transactivation assay）； systemic administration suppresses food intake and reduces weight gain in rats （10 mg/kg intraperitoneally） and PPARα wild type mice， but not in PPARα knockout mice

保存建議

建議您在收到開曼生物品牌的Oleoyl Ethanolamide （5 mg）產品后置于-20度保存，產品有效期為365天.

其他

開曼生物向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為開曼生物在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供的開曼生物產品以及客戶訂制化服務.