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當(dāng)前位置：上海泛柯實(shí)業(yè)有限公司>>抗體>>一抗>>FITC標(biāo)記的三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白2抗體

FITC標(biāo)記的三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白2抗體

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FITC標(biāo)記的三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白2抗體產(chǎn)品介紹：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

詳細(xì)介紹

英文名稱Anti-ABCA2/FITC
中文名稱FITC標(biāo)記的三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白2抗體
別    名ABC2; ATP binding cassette 2; ATP binding cassette sub family A member 2; ATP binding cassette transporter 2; ATP binding cassette, sub family A (ABC1), member 2; ATP binding cassette, sub family A, member 2; ATP binding cassette, sub family B (MDR/TAP), member 2;ABCA2_HUMAN.
說(shuō) 明 書100ul  
研究領(lǐng)域心血管  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat, Dog, Cow, Horse, 
產(chǎn)品應(yīng)用IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量270kDa
細(xì)胞定位細(xì)胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ABCA2
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene (from EntrezGene).

Function:
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.

Subcellular Location:
Endosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.

Tissue Specificity:
Highy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.

Similarity:
Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains.


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