| 英文名稱 | Anti-ANKRD53/FITC |
| 中文名稱 | FITC標記的錨蛋白重復域53抗體 |
| 別 名 | ANKRD 53; ANKRD53; Ankyrin repeat domain containing protein 53; Ankyrin repeat domain-containing protein 53; ANR53_HUMAN; FLJ12056. |
| 說 明 書 | 100ul |
| 研究領域 | 細胞生物 免疫學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Mouse, Rat, |
| 產品應用 | IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANKRD54 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 | background:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD53 (ankyrin repeat domain 53) is a 530 amino acid protein that contains three ANK repeats. Conserved in chimpanzee, dog, cow, mouse and zebrafish, ANKRD53 is encoded by a gene that maps to human chromosome 2p13.3. As the second largest human chromosome, chromosome 2 makes up approximay 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial omeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
Similarity:
Contains 4 ANK repeats. |
