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人組織細胞淋巴瘤細胞描述:U-937細胞系由Sundstrom和Nilsson在1974年建立,取材于患組織細胞淋巴瘤病人的胸水。 研究表明:U-937細胞能被人混合淋巴細胞培養上清,佛波脂、*3、γ干擾素、腫瘤壞死因子和維甲酸誘導終末單核細胞分化。 該細胞免疫球蛋白產物和EB病毒表達為陰性。 該細胞表達Fas抗原且對TNF和抗-Fas抗體敏感。
細胞名稱 | U-937人組織細胞淋巴瘤細胞 |
描述 | U-937細胞系由Sundstrom和Nilsson在1974年建立,取材于患組織細胞淋巴瘤病人的胸水。 研究表明:U-937細胞能被人混合淋巴細胞培養上清,佛波脂、*3、γ干擾素、腫瘤壞死因子和維甲酸誘導終末單核細胞分化。 該細胞免疫球蛋白產物和EB病毒表達為陰性。 該細胞表達Fas抗原且對TNF和抗-Fas抗體敏感。 |
動物種別 | 人 |
性別 | 男 |
組織來源 | 組織細胞淋巴瘤 |
形態 | 單核細胞 |
培養基和添加劑 | RPMI-1640(GIBCO,貨號31800022, 添加NaHCO3 1.5g/L, glucose 2.5g/L, Sodium Pyruvate 0.11g/L),90%;優質胎牛血清,10%。 氣相:空氣,95%;二氧化碳,5%。 溫度:37攝氏度。 |
供應限制 | A。僅供研究之用。 |
REFERENCE | Sundstrom C and Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer 17:565-577, 1976 PubMed: 76189427 Ralph P , et al. Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. J. Exp. Med. 143: 1528-1533, 1976. PubMed: 1083890 Gene expression during normal and malignant differentiation. 143: London: Academic Press; 1985, pp. 57-72. International symposium on new trends in human immunology and cancer immunotherapy. Paris: Doin Editeurs; 1980, pp. 271-292. Koren HS , et al. In vitro activation of a human macrophage-like cell line. Nature 279: 328-331, 1979. PubMed: 450085 Gidlund M , et al. Natural killer cells kill tumour cells at a given stage of differentiation. Nature 292: 848-850, 1981. PubMed: 7266653 Olsson I , et al. Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1 alpha,25-dihydroxycholecalciferol. Cancer Res. 43: 5862-5867, 1983. PubMed:6315218 Morimoto H , et al. Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins. Cancer Res. 53: 2591-2596, 1993. PubMed: 7684321 Giovannangeli C , et al. Accessibility of nuclear DNA to triplex-forming oligonucleotides: The integrated HIV-1 provirus as a target. Proc. Natl. Acad. Sci. USA 94: 79-84, 1997. PubMed: 8990164 Brigino E , et al. Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway. Proc. Natl. Acad. Sci. USA 94: 3178-3182, 1997. PubMed: 9096366 Reid YA , et al. Cell Line Cross-contamination of U-937. J. Leukocyte Biol. 57: 804, 1995. PubMed: 7759961 Sundstrom C , Nilsson K . Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer 17: 565-577, 1976. PubMed: 178611 Hay, R. J., Caputo, J. L, and Macy, M. L., Eds. (1992), ATCC Quality Control Methods for Cell Lines. 2nd edition, Published by ATCC. Caputo, J. L., Biosafety procedures in cell culture. J. Tissue Culture Methods 11:223-227. 1988. Fleming, D.O., Richardson, J. H., TuIis, J.J. and Vesley, D., (1995) Laboratory Safety: Principles and Practice. Second edition, ASM press, Washington, DC. Centers for Disease Control (1993), Biosafety in Microbiological and Biomedical Laboratories Human Health Service Publication No. (CDC) 93-8395. U.S. Dept. of Health and Human Services; 3rd Edition U.S. Government Printing Office Washington D.C. |
中文名稱 | 人組織細胞淋巴瘤細胞 |
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