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華瑞科研網-ELISA試劑盒
“Anti-CRTAP抗體,軟骨相關蛋白CRTAP抗體科研“我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!
Anti-CRTAP抗體,軟骨相關蛋白CRTAP抗體科研產品介紹:
CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.
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產品詳情:
產品編號:HRK-12949R
產品規格: 0.1ml/0.2ml
產品別名:Cartilage associated protein; LEPREL3; leprecan-like 3; CASP; CRTAP_HUMAN
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存: 貯存于-20℃.
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