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Anti-CPLX2抗體,Complexin II/復(fù)合素2抗體科研

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聯(lián)系人:韓經(jīng)理 (銷售)

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“Anti-CPLX2抗體,Complexin II/復(fù)合素2抗體科研“我公司擁有*的細(xì)胞服務(wù)技術(shù),*的儀器設(shè)備和專業(yè)的ELISA檢測(cè)試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等,廣泛用于多種分析研究與技術(shù)測(cè)定。咨詢,我們將竭誠(chéng)為你服務(wù)!

詳細(xì)介紹

Anti-CPLX2抗體,Complexin II/復(fù)合素2抗體科研產(chǎn)品介紹:

Complexin 1 and Complexin 2, also designated Synaphin 1 and Synaphin 2, contain an a-helical middle domain of approximay 58 amino acids. Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, respectively, and in cytoplasmic pools during early stages of development. Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain. Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediay after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion. Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation. A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, an autosomal dominant neurodegenerative disorder. Changes in the neurotransmitter release might contribute to the motor, emotional and cognitive dysfunctions seen in these mice. 


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產(chǎn)品詳情:
產(chǎn)品編號(hào):HRK-11342R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名:Complexin 2; Complexin II; Complexin-2; Complexin2; ComplexinII; CPLX 2; Cplx2; CPLX2_HUMAN; CPX 2; CPX II; CPXII; Hfb1; Synaphin 1; Synaphin-1; Synaphin1; 921 L
產(chǎn)品價(jià)格:詢價(jià)(電詢或客服)
產(chǎn)品用途:科研實(shí)驗(yàn)
貯 存:   貯存于-20℃.

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