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Anti-phospho-CstF64(Ser83),磷酸化細胞分裂相關蛋白CSTF64抗體科研

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“Anti-phospho-CstF64(Ser83),磷酸化細胞分裂相關蛋白CSTF64抗體科研“我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!

詳細介紹

Anti-phospho-CstF64(Ser83),磷酸化細胞分裂相關蛋白CSTF64抗體科研產品介紹:

Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF. CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, but not meiotic, germ cells. However, a large variant of CstF-64, called t CstF-64, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, and promotes the germ cell pattern of polyadenylation. The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, whereas t CstF-64 is encoded by an autosomal gene. The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation. 


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Anti-phospho-CstF64(Ser83),磷酸化細胞分裂相關蛋白CSTF64抗體科研產品詳情:
產品編號:HRK-8522R
產品規格: 0.1ml/0.2ml
產品別名:p-CstF-64 (Ser83); p-CstF-64 (S83); CstF64 (phospho-Ser83); CstF64 (phospho-S83); CSTF2T; CF1 64 kDa subunit, tau variant; Cleavage stimulation factor 64 kDa subunit, tau variant; CSTF 64 kDa subunit, tau variant; KIAA0689; TauCstF64; CSTF2_HUMAN
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存:   貯存于-20℃.

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