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Anti-phospho-CDKN1A (Ser130)抗體,磷酸化p21蛋白抗體科研

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更新時間:2018-05-14 09:38:00瀏覽次數:312次

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“Anti-phospho-CDKN1A (Ser130)抗體,磷酸化p21蛋白抗體科研“我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!

詳細介紹

Anti-phospho-CDKN1A (Ser130)抗體,磷酸化p21蛋白抗體科研產品介紹:

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.


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Anti-phospho-CDKN1A (Ser130)抗體,磷酸化p21蛋白抗體科研產品詳情:
產品編號:HRK-5274R
產品規格: 0.1ml/0.2ml
產品別名:Activating Fragment 1; CAP20; Cation chloride cotransporter-interacting protein 1; CDK Interacting Protein 1; CDK-interacting protein 1; CDKI; CDKN 1; CDKN1; CDKN1A; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA 6; MDA-6; MDA6; Melanoma Differentiation Associated Protein 6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; p21CIP1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wildtype p53 Activating Fragment 1; Wildtype p53-activated fragment 1
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存:   貯存于-20℃.

與“Anti-phospho-CDKN1A (Ser130)抗體,磷酸化p21蛋白抗體科研"有關的其他產品:

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