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當前位置:華瑞科研網-ELISA試劑盒>>科研抗體>>科研一抗>>Anti-CD28抗體,CD28抗體科研

Anti-CD28抗體,CD28抗體科研

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更新時間:2018-05-08 05:16:15瀏覽次數:262次

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聯系人:韓經理 (銷售)

產品簡介

“Anti-CD28抗體,CD28抗體科研"我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!

詳細介紹

Anti-CD28抗體,CD28抗體科研產品介紹:

Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximay 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells. The first is mediated via the T cell receptor following its interaction with antigenic peptide MHC complexes, and the second is delivered by accessory or costimulating molecules through their counter receptors on T lymphocytes. CD28 bears structural homology to CTLA 4 which is expressed at very low levels on the surface of CD4+ and CD8+ peripheral blood cells only following activation. CD28 is the natural receptor for the B7/BB 1 ligand (CD80) a 55-60 kDa glycoprotein which is expressed on activated B lymphocytes, on dendritic cells and on interferon gamma treated monocytes. The binding of B7 1/BB 1 molecules to CD28 is involved in T lymphocyte activation and in the initiation and maintenance of chronic inflammation.  


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產品詳情:
產品編號:HRK-1297R
產品規格: 0.1ml/0.2ml
產品別名:CD 28; CD28 antigen; CD28 molecule; MGC138290; T cell antigen CD28; T cell specific surface glycoprotein; T cell specific surface glycoprotein CD28; Tp44
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存:   貯存于-20℃.

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